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BDBM50409014 CHEMBL50139

SMILES: Oc1cc(nc2cc3OCOc3cc12)-c1cccc(OC(=O)c2ccccc2)c1

InChI Key: InChIKey=LIXXNWFKABMGBZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50409014   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tubulin


(Sus scrofa (Pig))
BDBM50409014
PNG
(CHEMBL50139)
Show SMILES Oc1cc(nc2cc3OCOc3cc12)-c1cccc(OC(=O)c2ccccc2)c1
Show InChI InChI=1S/C23H15NO5/c25-20-11-18(24-19-12-22-21(10-17(19)20)27-13-28-22)15-7-4-8-16(9-15)29-23(26)14-5-2-1-3-6-14/h1-12H,13H2,(H,24,25)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 447n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization interacting at the colchicine binding site.


J Med Chem 43: 167-76 (2000)


Article DOI: 10.1021/jm990333a
BindingDB Entry DOI: 10.7270/Q2CV4JZB
More data for this
Ligand-Target Pair