BDBM50409527 CHEMBL2112283
SMILES CN(C)CCCN(C)CCNC(=O)[C@@H]1CCCN1S(=O)(=O)c1ccc(NNC(=O)NC2c3ccccc3CCc3ccccc23)c(c1)[N+]([O-])=O
InChI Key InChIKey=NSKPGTTUWOXHBF-HKBQPEDESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50409527
TargetB2 bradykinin receptor(Homo sapiens (Human))
Novartis Institute For Medical Sciences
Curated by ChEMBL
Novartis Institute For Medical Sciences
Curated by ChEMBL
Affinity DataKi: 0.790nMAssay Description:Displacement of [3H]BK (1 nM) from human Bradykinin receptor B2 expressed in Cos-7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10.7nMAssay Description:Inhibition of specific binding of [3H]-BK (1 nM) to rat Bradykinin receptor B2 by 50% in NG108-15 cell membranesMore data for this Ligand-Target Pair
TargetB2 bradykinin receptor(Homo sapiens (Human))
Novartis Institute For Medical Sciences
Curated by ChEMBL
Novartis Institute For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Antagonism of the [Ca2+] efflux actions of human Bradykinin receptor B2 (WI38 fibroblasts)More data for this Ligand-Target Pair
TargetB2 bradykinin receptor(Homo sapiens (Human))
Novartis Institute For Medical Sciences
Curated by ChEMBL
Novartis Institute For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Antagonism of the [Ca2+] efflux actions of human Bradykinin receptor B2 (SK-N-SH neuroblastoma)More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of Bradykinin receptor B2-mediated contractions of rat uterus smooth muscleMore data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Inhibition of increase in [Ca2+] efflux from NG108-15 cells caused by activation of rat Bradykinin receptor B2More data for this Ligand-Target Pair