BDBM50409628 CHEMBL5276381

SMILES Fc1ccc(CN2CC(CCN3CC(C3)N3CCOCC3)(CCC2=O)c2ccc(Cl)c(Cl)c2)cc1

InChI Key InChIKey=AALWUTFIDZBLOW-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50409628   

TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50409628(CHEMBL5276381)
Affinity DataIC50:  3.40nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of Neisseria gonorrhoeaMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50409628(CHEMBL5276381)
Affinity DataKd:  6nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50409628(CHEMBL5276381)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of Plasmodium bergheiMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))TBA
LigandPNGBDBM50409628(CHEMBL5276381)
Affinity DataIC50:  6.10nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails PubMed