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BDBM50409718 CHEMBL2112118

SMILES: Nc1nc(=O)n(cc1F)[C@@H]1CC(F)(F)[C@H](CO)O1

InChI Key: InChIKey=GASVLOLKVYHJRB-WDSKDSINSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50409718   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human immunodeficiency virus type 1 protease


(Human immunodeficiency virus type 1)
BDBM50409718
PNG
(CHEMBL2112118)
Show SMILES Nc1nc(=O)n(cc1F)[C@@H]1CC(F)(F)[C@H](CO)O1
Show InChI InChI=1S/C9H10F3N3O3/c10-4-2-15(8(17)14-7(4)13)6-1-9(11,12)5(3-16)18-6/h2,5-6,16H,1,3H2,(H2,13,14,17)/t5-,6-/m0/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 8.80E+3n/an/an/an/a



The University of Georgia

Curated by ChEMBL


Assay Description
Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50


J Med Chem 46: 3245-56 (2003)


Article DOI: 10.1021/jm0300274
BindingDB Entry DOI: 10.7270/Q20V8C6H
More data for this
Ligand-Target Pair