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BDBM50409863 CHEMBL129119

SMILES: Cc1cc(c(S)cc1Cl)S(=O)(=O)Nc1nnc(Nc2ccccc2)[nH]1

InChI Key: InChIKey=MOGUXFMGDHBSDL-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50409863   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human immunodeficiency virus type 1 integrase


(Human immunodeficiency virus 1)
BDBM50409863
PNG
(CHEMBL129119)
Show SMILES Cc1cc(c(S)cc1Cl)S(=O)(=O)Nc1nnc(Nc2ccccc2)[nH]1
Show InChI InChI=1S/C15H14ClN5O2S2/c1-9-7-13(12(24)8-11(9)16)25(22,23)21-15-18-14(19-20-15)17-10-5-3-2-4-6-10/h2-8,24H,1H3,(H3,17,18,19,20,21)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.62E+4n/an/an/an/an/an/a



University of Southern California

Curated by ChEMBL


Assay Description
Inhibitory activity against 3' processing by HIV integrase


J Med Chem 47: 385-99 (2004)


Article DOI: 10.1021/jm030378i
BindingDB Entry DOI: 10.7270/Q2M61MFX
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 integrase


(Human immunodeficiency virus 1)
BDBM50409863
PNG
(CHEMBL129119)
Show SMILES Cc1cc(c(S)cc1Cl)S(=O)(=O)Nc1nnc(Nc2ccccc2)[nH]1
Show InChI InChI=1S/C15H14ClN5O2S2/c1-9-7-13(12(24)8-11(9)16)25(22,23)21-15-18-14(19-20-15)17-10-5-3-2-4-6-10/h2-8,24H,1H3,(H3,17,18,19,20,21)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.26E+4n/an/an/an/an/an/a



University of Southern California

Curated by ChEMBL


Assay Description
Inhibitory activity against DNA strand transfer by HIV integrase


J Med Chem 47: 385-99 (2004)


Article DOI: 10.1021/jm030378i
BindingDB Entry DOI: 10.7270/Q2M61MFX
More data for this
Ligand-Target Pair