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BDBM50409967 CHEMBL196081

SMILES: O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(Cc3nc(cs3)-c3ccc(F)c(F)c3)cc2)cc1)c1ccccc1

InChI Key: InChIKey=ZEVDNNXLGPCLBE-HKBQPEDESA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50409967   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-3 adrenergic receptor


(Homo sapiens (Human))
BDBM50409967
PNG
(CHEMBL196081)
Show SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(Cc3nc(cs3)-c3ccc(F)c(F)c3)cc2)cc1)c1ccccc1
Show InChI InChI=1S/C32H29F2N3O3S2/c33-28-15-10-25(19-29(28)34)30-21-41-32(36-30)18-23-8-13-27(14-9-23)42(39,40)37-26-11-6-22(7-12-26)16-17-35-20-31(38)24-4-2-1-3-5-24/h1-15,19,21,31,35,37-38H,16-18,20H2/t31-/m0/s1
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PC cid
PC sid
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Similars

Article
PubMed
n/an/an/an/a 7.10n/an/an/an/a



S.G.S.I.T.S.

Curated by ChEMBL


Assay Description
Effective concentration to stimulate cAMP production in chinese hamster ovary cells expressing cloned human beta-3-adrenergic receptor


Bioorg Med Chem Lett 15: 3167-73 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.119
BindingDB Entry DOI: 10.7270/Q26111JS
More data for this
Ligand-Target Pair