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BDBM50410159 CHEMBL426092

SMILES: Oc1ccc(\C=C2\C(=O)Oc3ccc(O)cc23)cc1

InChI Key: InChIKey=OBAXSLNBFZJCNP-NTUHNPAUSA-N

Data: 2 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50410159   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Topoisomerase II alpha (HuTopoIIα)


(Homo sapiens (Human))
BDBM50410159
PNG
(CHEMBL426092)
Show SMILES Oc1ccc(\C=C2\C(=O)Oc3ccc(O)cc23)cc1
Show InChI InChI=1S/C15H10O4/c16-10-3-1-9(2-4-10)7-13-12-8-11(17)5-6-14(12)19-15(13)18/h1-8,16-17H/b13-7+
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>4.00E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase II activity


Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase I (Topo I)


(Homo sapiens (Human))
BDBM50410159
PNG
(CHEMBL426092)
Show SMILES Oc1ccc(\C=C2\C(=O)Oc3ccc(O)cc23)cc1
Show InChI InChI=1S/C15H10O4/c16-10-3-1-9(2-4-10)7-13-12-8-11(17)5-6-14(12)19-15(13)18/h1-8,16-17H/b13-7+
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.55E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase I activity


Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair