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BDBM50410303 CHEMBL361847

SMILES: CC(=O)N1c2ccc(NC(=O)c3ccc(cc3)C(F)(F)F)cc2C(C)(CC1(C)C)c1ccccc1

InChI Key: InChIKey=UWCKSOOAWYHHJL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50410303   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Follicle stimulating hormone receptor


(Homo sapiens (Human))
BDBM50410303
PNG
(CHEMBL361847)
Show SMILES CC(=O)N1c2ccc(NC(=O)c3ccc(cc3)C(F)(F)F)cc2C(C)(CC1(C)C)c1ccccc1
Show InChI InChI=1S/C28H27F3N2O2/c1-18(34)33-24-15-14-22(32-25(35)19-10-12-21(13-11-19)28(29,30)31)16-23(24)27(4,17-26(33,2)3)20-8-6-5-7-9-20/h5-16H,17H2,1-4H3,(H,32,35)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 7n/an/an/an/an/an/a



Research and Development

Curated by ChEMBL


Assay Description
In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptor


J Med Chem 48: 1697-700 (2005)


Article DOI: 10.1021/jm049676l
BindingDB Entry DOI: 10.7270/Q2VX0G0G
More data for this
Ligand-Target Pair