BDBM50410303 CHEMBL361847

SMILES: CC(=O)N1c2ccc(NC(=O)c3ccc(cc3)C(F)(F)F)cc2C(C)(CC1(C)C)c1ccccc1

InChI Key: InChIKey=UWCKSOOAWYHHJL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50410303   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Follicle stimulating hormone receptor (Homo sapiens (Human))	BDBM50410303 (CHEMBL361847) Show SMILES CC(=O)N1c2ccc(NC(=O)c3ccc(cc3)C(F)(F)F)cc2C(C)(CC1(C)C)c1ccccc1 Show InChI InChI=1S/C28H27F3N2O2/c1-18(34)33-24-15-14-22(32-25(35)19-10-12-21(13-11-19)28(29,30)31)16-23(24)27(4,17-26(33,2)3)20-8-6-5-7-9-20/h5-16H,17H2,1-4H3,(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Research and Development Curated by ChEMBL					Assay Description In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptor				J Med Chem 48: 1697-700 (2005) Article DOI: 10.1021/jm049676l BindingDB Entry DOI: 10.7270/Q2VX0G0G
					More data for this Ligand-Target Pair