BDBM50411655 CHEMBL408208

SMILES Cc1ccc2c(cccc2n1)-c1nnc(SCCN2CCc3cc4nc(oc4c(Br)c3CC2)C(F)(F)F)n1C

InChI Key InChIKey=KBAMXOZNCXYSJT-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50411655   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411655(CHEMBL408208)
Affinity DataKi:  316nMAssay Description:Antagonist activity at human dopamine D3 receptor by cell based GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411655(CHEMBL408208)
Affinity DataKi: >794nMAssay Description:Antagonist activity at dopamine D2 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411655(CHEMBL408208)
Affinity DataKi: >2.51E+3nMAssay Description:Antagonist activity at histamine H1 receptor by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411655(CHEMBL408208)
Affinity DataIC50:  631nMAssay Description:Displacement of [3H]Dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed