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BDBM50411837 CHEMBL414000

SMILES: Cc1cn2cccc2c(n1)C#Cc1ccc(F)cc1

InChI Key: InChIKey=KFJQJPZYEILGKB-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50411837   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50411837
PNG
(CHEMBL414000)
Show SMILES Cc1cn2cccc2c(n1)C#Cc1ccc(F)cc1
Show InChI InChI=1S/C16H11FN2/c1-12-11-19-10-2-3-16(19)15(18-12)9-6-13-4-7-14(17)8-5-13/h2-5,7-8,10-11H,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 15.8n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPR


Bioorg Med Chem Lett 18: 1804-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.024
BindingDB Entry DOI: 10.7270/Q27945W4
More data for this
Ligand-Target Pair