BDBM50412118 CHEMBL494806

SMILES CC(=O)Nc1cccc(CN2CCN(CCOc3cccc4nc(C)ccc34)CC2)c1

InChI Key InChIKey=PMUMPYZJZVTUOL-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50412118   

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412118(CHEMBL494806)
Affinity DataKi:  0.501nMAssay Description:Displacement of [3H]5HT from human recombinant 5HT1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412118(CHEMBL494806)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412118(CHEMBL494806)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]5HT from human recombinant 5HT1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412118(CHEMBL494806)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]WAY100635 from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412118(CHEMBL494806)
Affinity DataKi:  1.26E+3nMAssay Description:Inhibition of [3H]5HT uptake at SERT in rat cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed