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BDBM50412353 CHEMBL486848

SMILES: CCCCc1nc2cc(NC(=O)c3ccccc3Cl)ccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key: InChIKey=ZYRJMDMVFWCAJH-UHFFFAOYSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50412353   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
AGTR1


(RAT)
BDBM50412353
PNG
(CHEMBL486848)
Show SMILES CCCCc1nc2cc(NC(=O)c3ccccc3Cl)ccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C32H28ClN3O3/c1-2-3-12-30-35-28-19-23(34-31(37)26-10-6-7-11-27(26)33)17-18-29(28)36(30)20-21-13-15-22(16-14-21)24-8-4-5-9-25(24)32(38)39/h4-11,13-19H,2-3,12,20H2,1H3,(H,34,37)(H,38,39)
PDB

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Similars

Article
PubMed
n/an/an/a 316n/an/an/an/an/a



Punjabi University

Curated by ChEMBL


Assay Description
Antagonist activity at AT1 receptor in rat aorta


Eur J Med Chem 43: 1808-12 (2008)


Article DOI: 10.1016/j.ejmech.2007.11.008
BindingDB Entry DOI: 10.7270/Q2BZ679K
More data for this
Ligand-Target Pair