BDBM50413272 AC-261066::CHEMBL198997

SMILES CCCCOCCOc1nc(sc1C)-c1ccc(C(O)=O)c(F)c1

InChI Key InChIKey=HSAOETBFVAWNRP-UHFFFAOYSA-N

Data  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50413272   

TargetRetinoic acid receptor beta(Homo sapiens (Human))
Acadia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50413272(AC-261066 | CHEMBL198997)
Affinity DataEC50:  7.94nMAssay Description:Agonist activity at RARbeta2 expressed in mouse NIH3T3 cells by R-SAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Acadia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50413272(AC-261066 | CHEMBL198997)
Affinity DataEC50:  631nMAssay Description:Activity at RARalpha expressed in mouse NIH3T3 cells by R-SAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Acadia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50413272(AC-261066 | CHEMBL198997)
Affinity DataEC50:  398nMAssay Description:Activity at RARbeta1 expressed in mouse NIH3T3 cells by R-SAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Mus musculus)
King'S College

Curated by ChEMBL
LigandPNGBDBM50413272(AC-261066 | CHEMBL198997)
Affinity DataEC50:  70nMAssay Description:Transactivation of GAL4-fused mouse RARalpha-LBD expressed in COS-7 cells after 24 hrs by bright-Glo reagent based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Acadia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50413272(AC-261066 | CHEMBL198997)
Affinity DataEC50:  10nMAssay Description:Transcriptional activity against RARbeta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Mus musculus)
King'S College

Curated by ChEMBL
LigandPNGBDBM50413272(AC-261066 | CHEMBL198997)
Affinity DataEC50:  12nMAssay Description:Transactivation of GAL4-fused mouse RARbeta-LBD expressed in COS-7 cells after 24 hrs by bright-Glo reagent based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Mus musculus)
King'S College

Curated by ChEMBL
LigandPNGBDBM50413272(AC-261066 | CHEMBL198997)
Affinity DataEC50:  5.80nMAssay Description:Transactivation of GAL4-fused mouse RARgamma-LBD expressed in COS-7 cells after 24 hrs by bright-Glo reagent based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Acadia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50413272(AC-261066 | CHEMBL198997)
Affinity DataEC50:  501nMAssay Description:Activity at RARgamma expressed in mouse NIH3T3 cells by R-SAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed