BDBM50413373 CHEMBL502618

SMILES CCc1cc(Oc2cnc(N)nc2N)c(cc1OC)C(C)C

InChI Key InChIKey=GNXVOAVSOLSRGY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50413373   

TargetDihydrofolate reductase(Staphylococcus aureus)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50413373(CHEMBL502618)
Affinity DataIC50: 25nMAssay Description:Inhibition of Staphylococcus aureus DHFR expressed in Escherichia coli BL21 (DE3) using DHF as substrate preincubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetP2X purinoceptor 3(Rat)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50413373(CHEMBL502618)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at rat recombinant P2X3 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50413373(CHEMBL502618)
Affinity DataIC50: 158nMAssay Description:Inhibition of P2X2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed