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BDBM50413440 CHEMBL494151

SMILES: FC(F)(F)c1ccccc1C(=O)NCc1cccc(c1)-c1cccc(CN2CCNCC2)c1

InChI Key: InChIKey=RTCPIQVUPXWTSA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50413440   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50413440
PNG
(CHEMBL494151)
Show SMILES FC(F)(F)c1ccccc1C(=O)NCc1cccc(c1)-c1cccc(CN2CCNCC2)c1
Show InChI InChI=1S/C26H26F3N3O/c27-26(28,29)24-10-2-1-9-23(24)25(33)31-17-19-5-3-7-21(15-19)22-8-4-6-20(16-22)18-32-13-11-30-12-14-32/h1-10,15-16,30H,11-14,17-18H2,(H,31,33)
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Similars

Article
PubMed
n/an/a 3.98E+3n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobili...


Bioorg Med Chem Lett 19: 1686-90 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.098
BindingDB Entry DOI: 10.7270/Q2639QZ5
More data for this
Ligand-Target Pair