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BDBM50413456 CHEMBL495028

SMILES: CN1CCN(Cc2cccc(c2)C(=O)NCc2cccc(c2)-c2cccc(CN3CCNCC3)c2)CC1

InChI Key: InChIKey=AAADPBLPXCELKR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50413456   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50413456
PNG
(CHEMBL495028)
Show SMILES CN1CCN(Cc2cccc(c2)C(=O)NCc2cccc(c2)-c2cccc(CN3CCNCC3)c2)CC1
Show InChI InChI=1S/C31H39N5O/c1-34-15-17-36(18-16-34)24-27-7-4-10-30(21-27)31(37)33-22-25-5-2-8-28(19-25)29-9-3-6-26(20-29)23-35-13-11-32-12-14-35/h2-10,19-21,32H,11-18,22-24H2,1H3,(H,33,37)
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 3.98n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobili...


Bioorg Med Chem Lett 19: 1686-90 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.098
BindingDB Entry DOI: 10.7270/Q2639QZ5
More data for this
Ligand-Target Pair