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BDBM50413825 CHEMBL472690

SMILES: CCCN1CCN(CC1)c1ncc(CCN(C)Cc2ccccc2)s1

InChI Key: InChIKey=LPMNAUVSJOEGQM-UHFFFAOYSA-N

Data: 2 Kd

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50413825   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HRH3


(GUINEA PIG)
BDBM50413825
PNG
(CHEMBL472690)
Show SMILES CCCN1CCN(CC1)c1ncc(CCN(C)Cc2ccccc2)s1
Show InChI InChI=1S/C20H30N4S/c1-3-10-23-12-14-24(15-13-23)20-21-16-19(25-20)9-11-22(2)17-18-7-5-4-6-8-18/h4-8,16H,3,9-15,17H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 17.4n/an/an/an/an/a



Medical University

Curated by ChEMBL


Assay Description
Antagonist activity at histamine H3 receptor in guinea pig jejunum assessed as electrically evoked contractions


Eur J Med Chem 44: 1674-81 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.019
BindingDB Entry DOI: 10.7270/Q2VM4DGB
More data for this
Ligand-Target Pair
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50413825
PNG
(CHEMBL472690)
Show SMILES CCCN1CCN(CC1)c1ncc(CCN(C)Cc2ccccc2)s1
Show InChI InChI=1S/C20H30N4S/c1-3-10-23-12-14-24(15-13-23)20-21-16-19(25-20)9-11-22(2)17-18-7-5-4-6-8-18/h4-8,16H,3,9-15,17H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a>1.00E+5n/an/an/an/an/a



Medical University

Curated by ChEMBL


Assay Description
Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as histamine-induced contractions


Eur J Med Chem 44: 1674-81 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.019
BindingDB Entry DOI: 10.7270/Q2VM4DGB
More data for this
Ligand-Target Pair