BDBM50413958 CHEMBL240177
SMILES COc1ncccc1NC(NC(NC(=O)c1ccc(Cl)cc1)C(C)(Cl)Cl)=NC#N
InChI Key InChIKey=PCYQNSRPJFTODK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50413958
Affinity DataIC50: 63.1nMAssay Description:Antagonist activity at human cloned P2X7 receptor expressed in HEK293 cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataEC50: 9.77E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50.1nMAssay Description:Antagonist activity at rat cloned P2X7 receptor expressed in HEK293 cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair