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BDBM50414498 CHEMBL550563

SMILES: OC(=O)c1cc([nH]n1)N(Cc1ccccc1F)Cc1ccccc1F

InChI Key: InChIKey=WRYLGVZPOKRCNP-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50414498   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HM74 nicotinic acid GPCR


(Homo sapiens (Human))
BDBM50414498
PNG
(CHEMBL550563)
Show SMILES OC(=O)c1cc([nH]n1)N(Cc1ccccc1F)Cc1ccccc1F
Show InChI InChI=1S/C18H15F2N3O2/c19-14-7-3-1-5-12(14)10-23(11-13-6-2-4-8-15(13)20)17-9-16(18(24)25)21-22-17/h1-9H,10-11H2,(H,21,22)(H,24,25)
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PC cid
PC sid
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Similars

Article
PubMed
n/an/an/an/a 8.71E+3n/an/an/an/a



Arena Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at GPR109b receptor transfected in CHOK1 cells assessed as inhibition of forskolin-induced cAMP generation by HTRF assay


Bioorg Med Chem Lett 19: 4207-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.108
BindingDB Entry DOI: 10.7270/Q2GF0TJJ
More data for this
Ligand-Target Pair