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BDBM50414686 CHEMBL552693

SMILES: COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CCCCCO)CC1

InChI Key: InChIKey=ZBZJLGMKLRNCSZ-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50414686   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 4 (5-HT4)


(Homo sapiens (Human))
BDBM50414686
PNG
(CHEMBL552693)
Show SMILES COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CCCCCO)CC1
Show InChI InChI=1S/C18H28ClN3O3/c1-25-17-12-16(20)15(19)11-14(17)18(24)21-13-5-8-22(9-6-13)7-3-2-4-10-23/h11-13,23H,2-10,20H2,1H3,(H,21,24)
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UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
63.1n/an/an/an/an/an/an/an/a



Theravance, Inc.

Curated by ChEMBL


Assay Description
Displacement of [H]GR-113808 from human 5HT4C receptor expressed in HEK293 cells by liquid scintillation counting


J Med Chem 52: 5330-43 (2009)


Article DOI: 10.1021/jm900881j
BindingDB Entry DOI: 10.7270/Q2CF9RBH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 4 (5-HT4)


(Homo sapiens (Human))
BDBM50414686
PNG
(CHEMBL552693)
Show SMILES COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CCCCCO)CC1
Show InChI InChI=1S/C18H28ClN3O3/c1-25-17-12-16(20)15(19)11-14(17)18(24)21-13-5-8-22(9-6-13)7-3-2-4-10-23/h11-13,23H,2-10,20H2,1H3,(H,21,24)
Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 15.8n/an/an/an/a



Theravance, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human 5HT4C receptor expressed in HEK293 cells assessed as acumulation of cAMP by flash plate adenylyl cyclase activation assay


J Med Chem 52: 5330-43 (2009)


Article DOI: 10.1021/jm900881j
BindingDB Entry DOI: 10.7270/Q2CF9RBH
More data for this
Ligand-Target Pair