BDBM50414936 CHEMBL120082::NSC-608475::US11753371, Compound I-2k

SMILES S=C(SSC(=S)N(Cc1ccccc1)Cc1ccccc1)N(Cc1ccccc1)Cc1ccccc1

InChI Key InChIKey=WITDFSFZHZYQHB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50414936   

TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Universite Catholique De Louvain

Curated by ChEMBL
LigandPNGBDBM50414936(CHEMBL120082 | NSC-608475 | US11753371, Compound I...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant FAAH-maltose binding proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Universite Catholique De Louvain

Curated by ChEMBL
LigandPNGBDBM50414936(CHEMBL120082 | NSC-608475 | US11753371, Compound I...)
Affinity DataIC50:  9.55E+3nMAssay Description:Inhibition of human MGL activity using [3H]2-oleoylglycerol substrate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Universite Catholique De Louvain

Curated by ChEMBL
LigandPNGBDBM50414936(CHEMBL120082 | NSC-608475 | US11753371, Compound I...)
Affinity DataIC50:  3.58E+3nMAssay Description:The compounds II-2a to II-2m and controls in Table II were tested in 10-dose IC50 mode, with 3-fold serial dilution at a starting concentration of 10...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))
Batterjee Medical College

US Patent
LigandPNGBDBM50414936(CHEMBL120082 | NSC-608475 | US11753371, Compound I...)
Affinity DataIC50: >1.00E+5nMAssay Description:5 μl of enzyme (150 nM for ALDH1a1 and 200 nM for ALDH2 in reaction buffer) were delivered to assay wells in coming black, 384 well plate. 5 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))
Batterjee Medical College

US Patent
LigandPNGBDBM50414936(CHEMBL120082 | NSC-608475 | US11753371, Compound I...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ALDH1A1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed