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BDBM50415399 CHEMBL601440

SMILES: CN(C(=O)c1c(C)onc1-c1cccc(F)c1)c1ccc(Cl)cc1

InChI Key: InChIKey=DMPXXMYUUVEGKT-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50415399   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled bile acid receptor 1


(Homo sapiens (Human))
BDBM50415399
PNG
(CHEMBL601440)
Show SMILES CN(C(=O)c1c(C)onc1-c1cccc(F)c1)c1ccc(Cl)cc1
Show InChI InChI=1S/C18H14ClFN2O2/c1-11-16(17(21-24-11)12-4-3-5-14(20)10-12)18(23)22(2)15-8-6-13(19)7-9-15/h3-10H,1-2H3
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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 7.94n/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human TGR5 receptor expressed in human U2-OS cells assessed as changes in response to cAMP level by MRE/CRE-driven luciferase rep...


Bioorg Med Chem Lett 20: 1363-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.003
BindingDB Entry DOI: 10.7270/Q2028SS5
More data for this
Ligand-Target Pair