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BDBM50415422 CHEMBL603921

SMILES: CC(C)c1onc(c1C(=O)N(C)c1ccc(Cl)cc1)-c1ccccc1Cl

InChI Key: InChIKey=SSJMSQSUZSSLPS-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50415422   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled bile acid receptor 1


(Homo sapiens (Human))
BDBM50415422
PNG
(CHEMBL603921)
Show SMILES CC(C)c1onc(c1C(=O)N(C)c1ccc(Cl)cc1)-c1ccccc1Cl
Show InChI InChI=1S/C20H18Cl2N2O2/c1-12(2)19-17(18(23-26-19)15-6-4-5-7-16(15)22)20(25)24(3)14-10-8-13(21)9-11-14/h4-12H,1-3H3
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 19.9n/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human TGR5 receptor expressed in human U2-OS cells assessed as changes in response to cAMP level by MRE/CRE-driven luciferase rep...


Bioorg Med Chem Lett 20: 1363-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.003
BindingDB Entry DOI: 10.7270/Q2028SS5
More data for this
Ligand-Target Pair