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BDBM50415519 CHEMBL591677

SMILES: CC(=O)N\N=c1/sc2cc(OC(F)(F)F)ccc2n1C

InChI Key: InChIKey=PINBTIXKIMTDHZ-YBEGLDIGSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50415519   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated potassium channel subunit Kv7.2/Kv7.3


(Homo sapiens (Human))
BDBM50415519
PNG
(CHEMBL591677)
Show SMILES CC(=O)N\N=c1/sc2cc(OC(F)(F)F)ccc2n1C
Show InChI InChI=1S/C11H10F3N3O2S/c1-6(18)15-16-10-17(2)8-4-3-7(5-9(8)20-10)19-11(12,13)14/h3-5H,1-2H3,(H,15,18)/b16-10-
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



Icagen, Inc.

Curated by ChEMBL


Assay Description
Activation of KCNQ2/KCNQ3 expressed in CHO cells by isotopic efflux assay


J Med Chem 53: 887-96 (2010)


Article DOI: 10.1021/jm901497b
BindingDB Entry DOI: 10.7270/Q2BC40TS
More data for this
Ligand-Target Pair