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BDBM50415604 CHEMBL1077116

SMILES: COc1cc2C(=NCCc2cc1Cl)c1cccc(Cl)c1

InChI Key: InChIKey=ZSBXRUMZMZJCRU-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50415604   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50415604
PNG
(CHEMBL1077116)
Show SMILES COc1cc2C(=NCCc2cc1Cl)c1cccc(Cl)c1
Show InChI InChI=1S/C16H13Cl2NO/c1-20-15-9-13-10(8-14(15)18)5-6-19-16(13)11-3-2-4-12(17)7-11/h2-4,7-9H,5-6H2,1H3
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.58E+4n/an/an/an/an/an/a



GlaxoSmithKline R&D

Curated by ChEMBL


Assay Description
Inhibition of histidine-tagged human recombinant p38alpha after 120 mins by TR-FRET assay


Bioorg Med Chem Lett 19: 2230-4 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.098
BindingDB Entry DOI: 10.7270/Q2Z320WR
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 10


(Homo sapiens (Human))
BDBM50415604
PNG
(CHEMBL1077116)
Show SMILES COc1cc2C(=NCCc2cc1Cl)c1cccc(Cl)c1
Show InChI InChI=1S/C16H13Cl2NO/c1-20-15-9-13-10(8-14(15)18)5-6-19-16(13)11-3-2-4-12(17)7-11/h2-4,7-9H,5-6H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.26E+4n/an/an/an/an/an/a



GlaxoSmithKline R&D

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His(6)-tagged truncated human JNK3 transfected in baculovirus expression system by fluorescence anisotropy


Bioorg Med Chem Lett 19: 2230-4 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.098
BindingDB Entry DOI: 10.7270/Q2Z320WR
More data for this
Ligand-Target Pair