BDBM50415616 CHEMBL1087421
SMILES COc1cc2CCN=C(c3ccc(Cl)c(Cl)c3)c2cc1Cl
InChI Key InChIKey=QLDFAHVPALXKAU-UHFFFAOYSA-N
Data 19 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 50415616
Affinity DataIC50: 316nMAssay Description:Inhibition of N-terminal His(6)-tagged truncated human JNK3 transfected in baculovirus expression system by fluorescence anisotropyMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal histidine-tagged human full length JNK1-alpha-1 by radiometric filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50.1nMAssay Description:Inhibition of N-terminal histidine-tagged human full length JNK3 by radiometric filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of N-terminal GST-tagged human full length Erk2 by radiometric filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of c-FmsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IKKalphaMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MLK3More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of SGK1More data for this Ligand-Target Pair
Affinity DataIC50: 794nMAssay Description:Inhibition of N-terminal histidine-tagged human full length JNK2-alpha-2 by radiometric filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of N-terminal GST-tagged p38alpha expressed in Escherichia coli by fluorescence anisotropyMore data for this Ligand-Target Pair