BindingDB logo
myBDB logout

BDBM50415673 CHEMBL1079187

SMILES: CCCCc1ccc(cc1)S(=O)(=O)Nc1ccc2CCN(Cc3cnc(C)[nH]3)CCc2c1

InChI Key: InChIKey=IEWQTFGFLPFFRK-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50415673   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Motilin receptor


(Homo sapiens (Human))
BDBM50415673
PNG
(CHEMBL1079187)
Show SMILES CCCCc1ccc(cc1)S(=O)(=O)Nc1ccc2CCN(Cc3cnc(C)[nH]3)CCc2c1
Show InChI InChI=1S/C25H32N4O2S/c1-3-4-5-20-6-10-25(11-7-20)32(30,31)28-23-9-8-21-12-14-29(15-13-22(21)16-23)18-24-17-26-19(2)27-24/h6-11,16-17,28H,3-5,12-15,18H2,1-2H3,(H,26,27)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 63.1n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant motilin receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 6452-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.027
BindingDB Entry DOI: 10.7270/Q2DV1K0C
More data for this
Ligand-Target Pair
Ghrelin receptor


(Homo sapiens (Human))
BDBM50415673
PNG
(CHEMBL1079187)
Show SMILES CCCCc1ccc(cc1)S(=O)(=O)Nc1ccc2CCN(Cc3cnc(C)[nH]3)CCc2c1
Show InChI InChI=1S/C25H32N4O2S/c1-3-4-5-20-6-10-25(11-7-20)32(30,31)28-23-9-8-21-12-14-29(15-13-22(21)16-23)18-24-17-26-19(2)27-24/h6-11,16-17,28H,3-5,12-15,18H2,1-2H3,(H,26,27)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 19.9n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human gherlin receptor


Bioorg Med Chem Lett 19: 6452-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.027
BindingDB Entry DOI: 10.7270/Q2DV1K0C
More data for this
Ligand-Target Pair