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BDBM50415793 CHEMBL1089744

SMILES: Cc1nn(C)c2ncc(C(=O)NCc3cc(C)cc(C)c3)c(Cl)c12

InChI Key: InChIKey=FOOBZQOGBXOHIF-UHFFFAOYSA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50415793   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50415793
PNG
(CHEMBL1089744)
Show SMILES Cc1nn(C)c2ncc(C(=O)NCc3cc(C)cc(C)c3)c(Cl)c12
Show InChI InChI=1S/C18H19ClN4O/c1-10-5-11(2)7-13(6-10)8-21-18(24)14-9-20-17-15(16(14)19)12(3)22-23(17)4/h5-7,9H,8H2,1-4H3,(H,21,24)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Medicines Research Centre

Curated by ChEMBL


Assay Description
Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of cortisol-induced renilla luciferase transactiv...


Bioorg Med Chem Lett 20: 2340-3 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.133
BindingDB Entry DOI: 10.7270/Q2SF2XDJ
More data for this
Ligand-Target Pair