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BDBM50416226 CHEMBL1083327

SMILES: FC(F)(F)c1cccc(c1)-c1ccccc1C(=O)NCC1CCNCC1

InChI Key: InChIKey=OHJZLVQSQPDTJH-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416226   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50416226
PNG
(CHEMBL1083327)
Show SMILES FC(F)(F)c1cccc(c1)-c1ccccc1C(=O)NCC1CCNCC1
Show InChI InChI=1S/C20H21F3N2O/c21-20(22,23)16-5-3-4-15(12-16)17-6-1-2-7-18(17)19(26)25-13-14-8-10-24-11-9-14/h1-7,12,14,24H,8-11,13H2,(H,25,26)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as effect on acetylcholine-induced intracellular calcium level by FL...


Bioorg Med Chem Lett 20: 3540-4 (2010)


Article DOI: 10.1016/j.bmcl.2010.04.128
BindingDB Entry DOI: 10.7270/Q2KP83DF
More data for this
Ligand-Target Pair