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BDBM50416247 CHEMBL1085513

SMILES: CN1CCC(CNC(=O)c2ccccc2-c2cccc(Cl)c2)CC1

InChI Key: InChIKey=PICKXKILPZYWHV-UHFFFAOYSA-N

Data: 1 EC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416247   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50416247
PNG
(CHEMBL1085513)
Show SMILES CN1CCC(CNC(=O)c2ccccc2-c2cccc(Cl)c2)CC1
Show InChI InChI=1S/C20H23ClN2O/c1-23-11-9-15(10-12-23)14-22-20(24)19-8-3-2-7-18(19)16-5-4-6-17(21)13-16/h2-8,13,15H,9-12,14H2,1H3,(H,22,24)
UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as effect on acetylcholine-induced intracellular calcium level by FL...


Bioorg Med Chem Lett 20: 3540-4 (2010)


Article DOI: 10.1016/j.bmcl.2010.04.128
BindingDB Entry DOI: 10.7270/Q2KP83DF
More data for this
Ligand-Target Pair