BDBM50416559 CHEMBL1160006::Ethane-1,1,2-Tricarboxylate

SMILES OC(=O)CC(C(O)=O)C(O)=O

InChI Key InChIKey=RWLDAJMGAVDXSH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50416559   

TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50416559(Ethane-1,1,2-Tricarboxylate | CHEMBL1160006)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHypoxia-inducible factor 1-alpha inhibitor(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50416559(Ethane-1,1,2-Tricarboxylate | CHEMBL1160006)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition of human FIH expressed in H5 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProlyl hydroxylase EGLN3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50416559(Ethane-1,1,2-Tricarboxylate | CHEMBL1160006)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of human PHD3 expressed in H5 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProlyl hydroxylase EGLN2(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50416559(Ethane-1,1,2-Tricarboxylate | CHEMBL1160006)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of human PHD1 expressed in H5 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetEgl nine homolog 1(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50416559(Ethane-1,1,2-Tricarboxylate | CHEMBL1160006)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of human PHD2 expressed in H5 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed