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BDBM50416913 CHEMBL1257836

SMILES: CCSc1nnc-2c(O[C@H](N(C(=O)CC)c3ccccc-23)c2ccco2)n1

InChI Key: InChIKey=QLBWSFDFXYAIPF-LGWFVXIRNA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416913   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor


(Rattus norvegicus (Rat))
BDBM50416913
PNG
(CHEMBL1257836)
Show SMILES CCSc1nnc-2c(O[C@H](N(C(=O)CC)c3ccccc-23)c2ccco2)n1
Show InChI InChI=1/C19H18N4O3S/c1-3-15(24)23-13-9-6-5-8-12(13)16-17(20-19(22-21-16)27-4-2)26-18(23)14-10-7-11-25-14/h5-11,18H,3-4H2,1-2H3/t18-/s2
PDB
MMDB

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Similars

Article
PubMed
n/an/an/an/a 813n/an/an/an/a



Vanderbilt University

Curated by ChEMBL


Assay Description
Inhibition of rat mGluR1 expressed in HEK293 cells


Bioorg Med Chem Lett 20: 5922-4 (2010)


Article DOI: 10.1016/j.bmcl.2010.07.061
BindingDB Entry DOI: 10.7270/Q2XS5WN3
More data for this
Ligand-Target Pair