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BDBM50417560 CHEMBL1642164

SMILES: OCc1cn(Cc2ccc3C[C@H](Cc3c2)NS(=O)(=O)C2CC2)nc1C(F)(F)F

InChI Key: InChIKey=OYEPHRNTXFDOML-GGYSOQFKNA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50417560   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
GRIA2


(Homo sapiens (Human))
BDBM50417560
PNG
(CHEMBL1642164)
Show SMILES OCc1cn(Cc2ccc3C[C@H](Cc3c2)NS(=O)(=O)C2CC2)nc1C(F)(F)F
Show InChI InChI=1/C18H20F3N3O3S/c19-18(20,21)17-14(10-25)9-24(22-17)8-11-1-2-12-6-15(7-13(12)5-11)23-28(26,27)16-3-4-16/h1-2,5,9,15-16,23,25H,3-4,6-8,10H2/t15-/s2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.51E+3n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Modulatory activity at GluA2 receptor LBD


Bioorg Med Chem Lett 21: 805-11 (2011)


Article DOI: 10.1016/j.bmcl.2010.11.098
BindingDB Entry DOI: 10.7270/Q2Q52QWZ
More data for this
Ligand-Target Pair