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BDBM50417574 CHEMBL1642155

SMILES: CC(C)S(=O)(=O)N[C@H]1Cc2ccc(Cn3nc(cc3C(F)(F)F)C(F)(F)F)cc2C1

InChI Key: InChIKey=HIPNHNLFGMETKO-AWEZNQCLSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50417574   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
GRIA2


(HUMAN)
BDBM50417574
PNG
(CHEMBL1642155)
Show SMILES CC(C)S(=O)(=O)N[C@H]1Cc2ccc(Cn3nc(cc3C(F)(F)F)C(F)(F)F)cc2C1
Show InChI InChI=1S/C18H19F6N3O2S/c1-10(2)30(28,29)26-14-6-12-4-3-11(5-13(12)7-14)9-27-16(18(22,23)24)8-15(25-27)17(19,20)21/h3-5,8,10,14,26H,6-7,9H2,1-2H3/t14-/m0/s1
PDB

UniProtKB/SwissProt

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AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 100n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Modulatory activity at GluA2 receptor LBD


Bioorg Med Chem Lett 21: 805-11 (2011)


Article DOI: 10.1016/j.bmcl.2010.11.098
BindingDB Entry DOI: 10.7270/Q2Q52QWZ
More data for this
Ligand-Target Pair