BDBM50418088 7-ETHYL-10-HYDROXY-CAMPTOTHECIN

SMILES: CCc1c2cc(ccc2nc3c1CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)O

InChI Key: InChIKey=FJHBVJOVLFPMQE-UHFFFAOYSA-N

Data: 1 KI  3 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50418088   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 1 (Human)	BDBM50418088 (7-ETHYL-10-HYDROXY-CAMPTOTHECIN) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50418088 (7-ETHYL-10-HYDROXY-CAMPTOTHECIN) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	176	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 1A1 (Human)	BDBM50418088 (7-ETHYL-10-HYDROXY-CAMPTOTHECIN) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM50418088 (7-ETHYL-10-HYDROXY-CAMPTOTHECIN) Show SMILES Show InChI	GoogleScholar	UniChem		2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair