BDBM50419670 CHEMBL1944691

SMILES O[C@@H](CNCCc1cccc(CNCCc2ccccc2F)c1)c1ccc(O)c2[nH]c(=O)sc12

InChI Key InChIKey=HIBBORWAHJKGBI-QHCPKHFHSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50419670   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419670(CHEMBL1944691)
Affinity DataEC50:  0.158nMAssay Description:Agonist activity at human beta2 adrenoceptor expressed in H292 cells assessed as increase in cAMP accumulation after 60 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419670(CHEMBL1944691)
Affinity DataIC50:  0.501nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419670(CHEMBL1944691)
Affinity DataIC50:  126nMAssay Description:Binding affinity to Alpha-1D adrenoceptor expressed in HEK cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419670(CHEMBL1944691)
Affinity DataEC50:  0.251nMAssay Description:Agonist activity at beta2 adrenoceptor in guinea pig trachea assessed as reduction in methacholine-induced contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419670(CHEMBL1944691)
Affinity DataIC50:  63nMAssay Description:Displacement of radiolabeled iodocyanopindolol from beta1 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419670(CHEMBL1944691)
Affinity DataIC50:  398nMAssay Description:Binding affinity to dopamine D2 receptor expressed in HEK cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed