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BDBM50420050 CHEMBL2046666

SMILES: Fc1ccc(cc1F)C(=O)Nc1ccc(NC2CC2)nc1

InChI Key: InChIKey=UPNSUDVNCSCKTP-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50420050   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated potassium channel subunit Kv7.2/Kv7.3


(Homo sapiens (Human))
BDBM50420050
PNG
(CHEMBL2046666)
Show SMILES Fc1ccc(cc1F)C(=O)Nc1ccc(NC2CC2)nc1
Show InChI InChI=1S/C15H13F2N3O/c16-12-5-1-9(7-13(12)17)15(21)20-11-4-6-14(18-8-11)19-10-2-3-10/h1,4-8,10H,2-3H2,(H,18,19)(H,20,21)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.70E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Agonist activity at KCNQ2/KCNQ3 expressed in CHO cells assessed as increase in KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induction ...


ACS Med Chem Lett 2: 481-484 (2011)


Article DOI: 10.1021/ml200053x
BindingDB Entry DOI: 10.7270/Q2R49RVJ
More data for this
Ligand-Target Pair