BDBM50420301 CHEMBL2089036

SMILES CC(C)[C@H](N)C(=O)OC[C@H](O)CNc1nc(NCc2ccc(cc2)-c2ccccn2)c2ncn(C(C)C)c2n1

InChI Key InChIKey=OOYQNTZOMNZRSG-GGAORHGYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50420301   

TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420301(CHEMBL2089036)
Affinity DataIC50:  180nMAssay Description:Inhibition of human recombinant CDK5/p25 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420301(CHEMBL2089036)
Affinity DataIC50:  180nMAssay Description:Inhibition of human recombinant CDK9/cyclin T expressed in baculovirus-infected insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50420301(CHEMBL2089036)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of mouse recombinant CLK1 expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50420301(CHEMBL2089036)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant DYRK1A expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420301(CHEMBL2089036)
Affinity DataIC50:  150nMAssay Description:Inhibition of CK1 after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed