BDBM50420563 CHEMBL2087023

SMILES COc1ccc(cc1)C(=O)Nc1ncc(s1)-c1ccc(cc1)C(O)=O

InChI Key InChIKey=UPIVZLFKYMNZDG-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50420563   

TargetCasein kinase II subunit alpha'(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50420563(CHEMBL2087023)
Affinity DataIC50:  11nMAssay Description:Inhibition of GST-tagged human CK2alpha' (1 to 350 residues) using CK2tide as substrate incubated for 1 hr by off-chip mobility shift assayMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50420563(CHEMBL2087023)
Affinity DataIC50:  20nMAssay Description:Inhibition of GST-tagged human CK2alpha (1 to 391 residues) using CK2tide as substrate incubated for 1 hr by off-chip mobility shift assayMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha'(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50420563(CHEMBL2087023)
Affinity DataIC50:  46nMAssay Description:Competitive inhibition of GST fused human CK2alpha' expressed in Escherichia coli BL21 after 10 mins in presence of ATPMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50420563(CHEMBL2087023)
Affinity DataIC50:  32nMAssay Description:Competitive inhibition of GST fused human CK2alpha expressed in Escherichia coli BL21 after 10 mins in presence of ATPMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50420563(CHEMBL2087023)
Affinity DataIC50:  20nMAssay Description:Inhibition of human CK2alpha (2 to 391 residues) using [33P]-ATP by scintillation counting based radioactive filter binding assayMore data for this Ligand-Target Pair