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BDBM50420821 CHEMBL2088047

SMILES: FCC(CN1CCC2(CC1)OCCc1ccsc21)Cc1ccccc1Cl

InChI Key: InChIKey=XKABXUBHCYDIDT-UHFFFAOYNA-N

Data: 1 KI

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50420821   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nociceptin receptor


(Homo sapiens (Human))
BDBM50420821
PNG
(CHEMBL2088047)
Show SMILES FCC(CN1CCC2(CC1)OCCc1ccsc21)Cc1ccccc1Cl
Show InChI InChI=1/C21H25ClFNOS/c22-19-4-2-1-3-18(19)13-16(14-23)15-24-9-7-21(8-10-24)20-17(5-11-25-21)6-12-26-20/h1-4,6,12,16H,5,7-11,13-15H2
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Similars

Article
PubMed
>10n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay


J Med Chem 55: 4955-67 (2012)


Article DOI: 10.1021/jm201629q
BindingDB Entry DOI: 10.7270/Q2TQ62SQ
More data for this
Ligand-Target Pair