BDBM50421506 CHEMBL61861::ORG-24598

SMILES CN(CC[C@@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1)CC([O-])=O

InChI Key InChIKey=KZWQAWBTWNPFPW-UHFFFAOYSA-M

Data  12 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50421506   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataIC50: 126nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity of compound towards Binding affinity towards Alpha-1A adrenergic receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity of compound towards serotonin 5-hydroxytryptamine 2C receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity of compound towards Dopamine receptor D2S was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity of compound towards serotonin 5-hydroxytryptamine 6 receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity of compound towards Beta-1 adrenergic receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity of compound towards Alpha-2C adrenergic receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity of compound towards serotonin 5-hydroxytryptamine 2A receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity of compound towards serotonin 5-hydroxytryptamine 7 receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Rat)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity of compound towards Dopamine receptor D4 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity of compound towards Beta-2 adrenergic receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:The compound was tested for the binding affinity towards Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed