BDBM50421517 CHEMBL450018

SMILES CCN(C)C(=O)c1ccccc1NCC1=NCCN1

InChI Key InChIKey=MJGIIZLIKBMVQO-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50421517   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421517(CHEMBL450018)
Affinity DataIC50:  2.04E+3nMAssay Description:Concentration required for 50% inhibition of binding against Alpha-1A adrenergic receptor in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421517(CHEMBL450018)
Affinity DataIC50:  6.76E+3nMAssay Description:Concentration required for 50% inhibition of binding against human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421517(CHEMBL450018)
Affinity DataEC50:  50nMAssay Description:Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421517(CHEMBL450018)
Affinity DataEC50:  631nMAssay Description:Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421517(CHEMBL450018)
Affinity DataEC50:  251nMAssay Description:Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421517(CHEMBL450018)
Affinity DataIC50:  1.05E+4nMAssay Description:Concentration required for 50% inhibition of binding against human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed