BDBM50421578 CHEMBL13789
SMILES C(Oc1ccccc1-c1ccccc1)C1=NCCN1
InChI Key InChIKey=BPRZPBVOIULUSI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50421578
Affinity DataKi: 2.30nMAssay Description:Binding affinity to I1 imidazoline binding site in Rattus norvegicus (rat) PC12 cellsMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 79nMAssay Description:Displacement of [3H]clonidine from Alpha-2 adrenergic receptor of rat cortex membraneMore data for this Ligand-Target Pair
Affinity DataKi: 302nMAssay Description:Displacement of [3H]idazoxan from imidazoline receptor I-2 binding sites in rabbit kidney membraneMore data for this Ligand-Target Pair
Affinity DataKi: 316nMAssay Description:Binding affinity for imidazoline receptor I-2 in rabbit kidney homogenate (relative to [3H]-Idazoxan radioligand)More data for this Ligand-Target Pair
Affinity DataEC50: <1.00E+5nMAssay Description:Activation of human alpha-1B adrenergic receptors expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:In vitro binding affinity against cloned human alpha-1B-adrenoreceptor receptors expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:In vitro binding affinity against cloned human alpha-1D-adrenoreceptor receptors expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:In vitro binding affinity against cloned human alpha-1A-adrenoreceptor receptors expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair
Affinity DataIC50: 741nMAssay Description:Binding affinity of compound towards human Alpha-1B adrenergic receptor expressed in rat fibroblast membranesChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 324nMAssay Description:Binding affinity of compound towards human Alpha-1D adrenergic receptor expressed in rat-1 fibroblast membranesChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Binding affinity of compound towards Alpha-1A adrenergic receptor using membranes prepared from Rat-1 fibroblasts expressing human Alpha-1A adrenergi...Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 3.20nMAssay Description:Activation of human alpha-1A adrenergic receptor expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair
Affinity DataEC50: <1.00E+5nMAssay Description:Activation of human Alpha-1D adrenergic receptors expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair
Affinity DataEC50: <1.00E+5nMAssay Description:Activation of recombinant human adrenergic, alpha-1B receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled P...Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 3.20nMAssay Description:Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: <1.00E+5nMAssay Description:Activation of recombinant human adrenergic, alpha-1D receptor expressed in rat-1 fibroblasts assayed via calcium mobilization through Gq coupled PLC ...Checked by AuthorMore data for this Ligand-Target Pair