BDBM50421580 CHEMBL117248
SMILES CSc1ccccc1NCC1=NCCN1
InChI Key InChIKey=YGIWTZGEYHABOR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50421580
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Affinity to human Alpha-1D adrenergic receptor determined by radioligand binding techniques from rat-1 fibroblasts membranesMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Affinity DataKi: 44nMAssay Description:Affinity to Alpha-1 adrenergic receptor determined by radioligand binding techniques from rat-1 fibroblasts membranesMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Affinity DataKi: 48nMAssay Description:Affinity to human Alpha-2A adrenergic receptor determined by radioligand binding techniques from chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Affinity DataKi: 66nMAssay Description:Affinity to human Alpha-1B adrenergic receptor determined by radioligand binding techniques from rat-1 fibroblasts membranesMore data for this Ligand-Target Pair
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Affinity DataKi: 145nMAssay Description:Affinity to human Alpha-2C adrenergic receptor determined by radioligand binding techniques from chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Affinity DataKi: 776nMAssay Description:Affinity to human Alpha-2B adrenergic receptor determined by radioligand binding techniques from chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:In vitro binding affinity against cloned human alpha-1D-adrenoreceptor receptors expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 8.90nMAssay Description:Agonist potency at Alpha-1D adrenergic receptor assayed in rat-1 fibroblastsMore data for this Ligand-Target Pair
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 2.20nMAssay Description:Agonist potency at alpha-1b adrenoceptors assayed in rat-1 fibroblasts expressing human alpha-1bMore data for this Ligand-Target Pair
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 5.60nMAssay Description:Agonist potency at Alpha-2C adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 219nMAssay Description:In vitro binding affinity against cloned human alpha-1B-adrenoreceptor receptors expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 40nMAssay Description:Agonist potency at Alpha-2A adrenergic receptor assayed in CHO cells expressing human alpha 2aMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 4.60nMAssay Description:Agonist potency at Alpha-1A adrenoceptors assayed in rat-1 fibroblasts expressing human Alpha-1AMore data for this Ligand-Target Pair
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 7.90nMAssay Description:Activation of human Alpha-1D adrenergic receptors expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 2nMAssay Description:Activation of human alpha-1B adrenergic receptors expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 107nMAssay Description:In vitro binding affinity against cloned human alpha-1A-adrenoreceptor receptors expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Glaxosmithkline Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 5nMAssay Description:Activation of human alpha-1A adrenergic receptor expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair