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BDBM50421604 ACH-126443::ELVUCITABINE

SMILES: Nc1nc(=O)n(cc1F)[C@H]1O[C@@H](CO)C=C1

InChI Key: InChIKey=HSBKFSPNDWWPSL-VDTYLAMSSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50421604   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50421604
PNG
(ACH-126443 | ELVUCITABINE)
Show SMILES Nc1nc(=O)n(cc1F)[C@H]1O[C@@H](CO)C=C1
Show InChI InChI=1S/C9H10FN3O3/c10-6-3-13(9(15)12-8(6)11)7-2-1-5(4-14)16-7/h1-3,5,7,14H,4H2,(H2,11,12,15)/t5-,7+/m1/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 140n/an/an/an/a



The University of Georgia

Curated by ChEMBL


Assay Description
In vitro antiviral activity against HIV-1 Reverse transcriptase M184V mutant


Bioorg Med Chem Lett 13: 1993-6 (2003)


Article DOI: 10.1016/s0960-894x(03)00330-5
BindingDB Entry DOI: 10.7270/Q2639Q86
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50421604
PNG
(ACH-126443 | ELVUCITABINE)
Show SMILES Nc1nc(=O)n(cc1F)[C@H]1O[C@@H](CO)C=C1
Show InChI InChI=1S/C9H10FN3O3/c10-6-3-13(9(15)12-8(6)11)7-2-1-5(4-14)16-7/h1-3,5,7,14H,4H2,(H2,11,12,15)/t5-,7+/m1/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 180n/an/an/an/a



The University of Georgia

Curated by ChEMBL


Assay Description
In vitro antiviral activity against HIV-1 Reverse transcriptase wild type


Bioorg Med Chem Lett 13: 1993-6 (2003)


Article DOI: 10.1016/s0960-894x(03)00330-5
BindingDB Entry DOI: 10.7270/Q2639Q86
More data for this
Ligand-Target Pair