BDBM50421673 CHEMBL5283441
SMILES COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OCCCCN1C(=O)c2ccccc2C1=O
InChI Key InChIKey=JCYZLTRHOBCBBR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50421673
Affinity DataKi: 290nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PknB (1 to 331 residues) expressed in Escherichia coli BL21-Rosetta cells using GarA and ATP as ...More data for this Ligand-Target Pair
Affinity DataKd: 48nMAssay Description:Binding affinity to Mycobacterium tuberculosis recombinant N-terminal His-tagged PknB (1 to 331 residues) expressed in Escherichia coli DH5alpha cell...More data for this Ligand-Target Pair
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human Cdk2/Cyclin A using Myelin basic protein as substrate by ATP competitive assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.20E+3nMAssay Description:Binding affinity to human partial length Pim1 (A15 to K313 residues ) expressed in bacterial expression system by KdELECT kinase assayMore data for this Ligand-Target Pair
Affinity DataKd: 440nMAssay Description:Binding affinity to human full length CDK4 (M1 to E303 residues) expressed in mammalian expression system/CyclinD3 by KdELECT kinase assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.60E+3nMAssay Description:Binding affinity to human full length GSK-3 beta (M1 to T433 residues) expressed in mammalian expression system by KdELECT kinase assayMore data for this Ligand-Target Pair
Affinity DataKd: 690nMAssay Description:Binding affinity to human partial length mTOR (L1382 to W2549 residues) expressed in mammalian expression system by KdELECT kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PknB (1 to 331 residues) expressed in Escherichia coli BL21-Rosetta cells using GarA and ATP as ...More data for this Ligand-Target Pair
Affinity DataKd: 47nMAssay Description:Binding affinity to Mycobacterium tuberculosis partial length PknB (M1 to G279 residues) expressed in mammalian expression system by KdELECT kinase a...More data for this Ligand-Target Pair