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TENIDAP CHEBI:1348726::CP-66248::Tenidap

Data: 3 IC50

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Other Databases links: CHEBI PubChem cid PubChem sid

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50421883    Zinc 0: unavailable per Zinc DB. Zinc 1: purchasable, 2 weeks to supply. Zinc 2: made on demand. Zinc 4: potentially available
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclooxygenase-1


(Oryctolagus cuniculus)
TENIDAP
PNG
(CHEBI:1348726 | CP-66248 | Tenidap)
Show SMILES NC(=O)N1C(=O)\C(=C(/O)c2cccs2)c2cc(Cl)ccc12
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
ChEBI
PC cid
PC sid
AffyNet 
Article
PubMed
n/an/a 2560.0n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of COX-1 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs by HPLC in presence of c...


Citation and Details

More data for this
Ligand-Target Pair
Arachidonate 5-lipoxygenase


(Rattus norvegicus)
TENIDAP
PNG
(CHEBI:1348726 | CP-66248 | Tenidap)
Show SMILES NC(=O)N1C(=O)\C(=C(/O)c2cccs2)c2cc(Cl)ccc12
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
ChEBI
PC cid
PC sid
AffyNet 
Article
PubMed
n/an/a 9000.0n/an/an/an/an/an/a



Pfizer Central Research

Curated by ChEMBL


Assay Description
In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cells


Citation and Details

More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Oryctolagus cuniculus)
TENIDAP
PNG
(CHEBI:1348726 | CP-66248 | Tenidap)
Show SMILES NC(=O)N1C(=O)\C(=C(/O)c2cccs2)c2cc(Cl)ccc12
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
ChEBI
PC cid
PC sid
AffyNet 
Article
PubMed
n/an/a 8400.0n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of COX-2 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs in by HPLC presence of c...


Citation and Details

More data for this
Ligand-Target Pair