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BDBM50421947 CHEMBL1743993

SMILES: C(N1CCC2(CCCc3ccccc23)CC1)c1ccco1

InChI Key: InChIKey=STKWGAGBCCGWRX-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50421947   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50421947
PNG
(CHEMBL1743993)
Show SMILES C(N1CCC2(CCCc3ccccc23)CC1)c1ccco1
Show InChI InChI=1S/C19H23NO/c1-2-8-18-16(5-1)6-3-9-19(18)10-12-20(13-11-19)15-17-7-4-14-21-17/h1-2,4-5,7-8,14H,3,6,9-13,15H2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.5n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity against sigma receptor by using [3H]-DTG ([3H]-6) as radioligand in guinea pig cerebellum.


J Med Chem 35: 2033-9 (1992)


Article DOI: 10.1021/jm00089a013
BindingDB Entry DOI: 10.7270/Q2GX4CVJ
More data for this
Ligand-Target Pair