BDBM50422542 Keppra::Keppra Xr::LEVETIRACETAM::Levetiracetam In Sodium Chloride::UCB-22059::UCB-L059

SMILES CC[C@@H](C(=O)N)N1CCCC1=O

InChI Key InChIKey=HPHUVLMMVZITSG-UHFFFAOYSA-N

Data  6 IC50

PDB links: 7 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50422542   

TargetCarbonic anhydrase 12(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  54nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetCarbonic anhydrase 9(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  89nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetSynaptic vesicle glycoprotein 2A(Rat)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataIC50: 794nMAssay Description:In vitro inhibitory activity against [3H](2S)-2-[4-(3-azidophenyl)-2-oxopyrrolidin-1-yl]butanamide binding to levetiracetam binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 14(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  2.27E+3nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetCarbonic anhydrase 3(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  2.44E+3nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  3.86E+3nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetCarbonic anhydrase 2(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  3.92E+3nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetCarbonic anhydrase 13(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  4.17E+3nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetCarbonic anhydrase 4(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetCarbonic anhydrase 7(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  7.55E+3nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetCarbonic anhydrase 1(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  7.95E+3nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetCarbonic anhydrase 6(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  8.40E+3nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataKi:  9.20E+3nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422542BDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed