BDBM50422689 640/359::CEFUROXIME

SMILES: CO/N=C(/c1ccco1)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)COC(=O)N)C(=O)O

InChI Key: InChIKey=JFPVXVDWJQMJEE-UHFFFAOYSA-N

Data: 6 KI  29 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 32 hits for monomerid = 50422689   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Penicillin-binding protein 2x (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	47.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Penicillin-binding protein 1A (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 1A (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.43	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 2x (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 2x (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0940	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 2x (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 1A (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 1A (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.43	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 1A (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	386	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	89.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	402	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 2x (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.71	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 1A (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.71	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 1A (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 1A (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.36	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 1A (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	54.2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 2x (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.07	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 2x (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.43	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Penicillin-binding protein 2x (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
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Glutathione reductase, mitochondrial (Human)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		1.04E+4	n/a	1.88E+4	n/a	n/a	n/a	n/a	8.0	n/a
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Microsomal glutathione S-transferase 1 (Human)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		3.24E+4	n/a	5.64E+4	n/a	n/a	n/a	n/a	6.5	n/a
TBA									Citation and Details
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Glutathione peroxidase 1 (Human)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		3.27E+4	n/a	4.43E+4	n/a	n/a	n/a	n/a	7.0	n/a
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					More data for this Ligand-Target Pair
Solute carrier family 15 member 1 (Human)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		2.60E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 15 member 2 (Human)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		1.26E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Solute carrier family 15 member 2 (Human)	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES Show InChI	GoogleScholar	UniChem		1.26E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair